Summary
AssigneeShanghai Helioson Pharmaceutical
Filing years2024-2025
Patents3
Compounds177
Activity records206
Patent families2
Targets5
Assay familiesbiochemical, degradation, viability
Activity metricsDC50, Dmax, IC50, fold_change
Overview

Target distribution and active-compound trend

Target distribution

285 activity records

6 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

07715420252026
Activity compounds and values

Activity records

285 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C025599
Dmax-=73.6%--IKZF1-NCI-H929CA3286762A1PGDB_A007207PGDB_C025599PGDB_AS000833View
2D structure for PGDB_C025649
IC50-=0.2nM---NCI-H929CA3286762A1PGDB_A008505PGDB_C025649PGDB_AS001402View
2D structure for PGDB_C025617
DC50-=0.077nM-IKZF1-NCI-H929CA3286762A1PGDB_A008513PGDB_C025617PGDB_AS002338View
2D structure for PGDB_C021276
IC50-=0.01nM---NCI-H929CA3286762A1PGDB_A008877PGDB_C021276PGDB_AS001402View
2D structure for PGDB_C021277
IC50-=0.01nM---NCI-H929CA3286762A1PGDB_A009349PGDB_C021277PGDB_AS001402View
2D structure for PGDB_C025600
IC50-=0.03nM---NCI-H929CA3286762A1PGDB_A009678PGDB_C025600PGDB_AS001402View
2D structure for PGDB_C025617
Dmax-=77.1%--IKZF3-NCI-H929CA3286762A1PGDB_A009731PGDB_C025617PGDB_AS001097View
2D structure for PGDB_C025597
Dmax-=71.4%--IKZF3-NCI-H929CA3286762A1PGDB_A010422PGDB_C025597PGDB_AS001097View
2D structure for PGDB_C025616
Dmax-=76.4%--IKZF3-NCI-H929CA3286762A1PGDB_A010531PGDB_C025616PGDB_AS001097View
2D structure for PGDB_C025672
IC50-=1.6nM---NCI-H929CA3286762A1PGDB_A011354PGDB_C025672PGDB_AS001402View
2D structure for PGDB_C025599
DC50-=0.081nM-IKZF1-NCI-H929CA3286762A1PGDB_A011550PGDB_C025599PGDB_AS002338View
2D structure for PGDB_C025638
IC50-=0.01nM---NCI-H929CA3286762A1PGDB_A011843PGDB_C025638PGDB_AS001402View
2D structure for PGDB_C025633
IC50-=0.01nM---NCI-H929CA3286762A1PGDB_A012196PGDB_C025633PGDB_AS001402View
2D structure for PGDB_C025607
IC50-=0.05nM---NCI-H929CA3286762A1PGDB_A012614PGDB_C025607PGDB_AS001402View
2D structure for PGDB_C025661
IC50-=0.07nM---NCI-H929CA3286762A1PGDB_A013928PGDB_C025661PGDB_AS001402View
2D structure for PGDB_C025597
DC50-=0.12nM-IKZF3-NCI-H929CA3286762A1PGDB_A014395PGDB_C025597PGDB_AS000521View
2D structure for PGDB_C025663
IC50-=0.04nM---NCI-H929CA3286762A1PGDB_A014439PGDB_C025663PGDB_AS001402View
2D structure for PGDB_C025600
DC50-=0.19nM-IKZF3-NCI-H929CA3286762A1PGDB_A014746PGDB_C025600PGDB_AS000521View
2D structure for PGDB_C025616
Dmax-=65.3%--IKZF1-NCI-H929CA3286762A1PGDB_A015525PGDB_C025616PGDB_AS000833View
2D structure for PGDB_C025659
IC50-=0.03nM---NCI-H929CA3286762A1PGDB_A015834PGDB_C025659PGDB_AS001402View