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Compound
PGDB_C019593
6 activity records1 related patents
2D structure
NC(=O)CCC(C(N)=O)N1Cc2cc(CN3CC[C@H](n4nc(-c5ccc(Oc6ccccc6)cc5)c5c(N)ncnc54)[C@@H](F)C3)ccc2C1=OCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | < | 50 | nM | - | — | BTK | CRBN | Mino | CN116239566A | PGDB_A018292 | PGDB_C019593 | PGDB_AS000540 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | MDA-MB-231 | CN116239566A | PGDB_A022433 | PGDB_C019593 | PGDB_AS001770 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | CRBN | 22Rv1 | CN116239566A | PGDB_A037219 | PGDB_C019593 | PGDB_AS001253 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | MM.1S | CN116239566A | PGDB_A064585 | PGDB_C019593 | PGDB_AS002551 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | JeKo-1 | CN116239566A | PGDB_A064898 | PGDB_C019593 | PGDB_AS000420 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | NCI-H1975 | CN116239566A | PGDB_A071911 | PGDB_C019593 | PGDB_AS000844 | View |