Summary
AssigneeNanjing Sanhome Pharmaceutical
Filing years2023-2025
Patents5
Compounds101
Activity records152
Patent families5
Targets3
Assay familiesbinding, biochemical, degradation, selectivity, viability
Activity metricsDC50, Dmax, IC50, degradation, inhibition
Overview

Target distribution and active-compound trend

Target distribution

165 activity records

4 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

02345202420252026
Activity compounds and values

Activity records

165 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C001454
IC50-=23.53nM-GSPT1-NCI-H1155CN118852145APGDB_A007000PGDB_C001454PGDB_AS001039View
2D structure for PGDB_C001466
IC50-=23.1nM-GSPT1-NCI-H1155CN118852145APGDB_A007688PGDB_C001466PGDB_AS001039View
2D structure for PGDB_C001469
IC50-=21.8nM-GSPT1-NCI-H1155CN118852145APGDB_A007709PGDB_C001469PGDB_AS001039View
2D structure for PGDB_C001475
IC50-=316.86nM-CRBNCRBN-CN118852145APGDB_A008335PGDB_C001475PGDB_AS000570View
2D structure for PGDB_C001476
IC50-=25.4nM-GSPT1-NCI-H1155CN118852145APGDB_A009346PGDB_C001476PGDB_AS001039View
2D structure for PGDB_C001468
IC50-=333.25nM-CRBNCRBN-CN118852145APGDB_A012014PGDB_C001468PGDB_AS000570View
2D structure for PGDB_C001467
IC50-=11.9nM-GSPT1-NCI-H1155CN118852145APGDB_A012720PGDB_C001467PGDB_AS001039View
2D structure for PGDB_C001473
IC50-=586.2nM-GSPT1-NCI-H1155CN118852145APGDB_A012936PGDB_C001473PGDB_AS001039View
2D structure for PGDB_C001465
IC50-=25.4nM-GSPT1-NCI-H1155CN118852145APGDB_A015479PGDB_C001465PGDB_AS001039View
2D structure for PGDB_C001468
Dmax-=93.1%--GSPT1-HEK293CN118852145APGDB_A016560PGDB_C001468PGDB_AS002339View
2D structure for PGDB_C001470
IC50-=322.59nM-CRBNCRBN-CN118852145APGDB_A017444PGDB_C001470PGDB_AS000570View
2D structure for PGDB_C001484
IC50-=756.73nM-CRBNCRBN-CN118852145APGDB_A017562PGDB_C001484PGDB_AS000570View
2D structure for PGDB_C001471
IC50-=119.97nM-CRBNCRBN-CN118852145APGDB_A018386PGDB_C001471PGDB_AS000570View
2D structure for PGDB_C001461
IC50-=20.28nM-GSPT1-NCI-H1155CN118852145APGDB_A019181PGDB_C001461PGDB_AS001039View
2D structure for PGDB_C001468
IC50-=5.7nM-GSPT1-NCI-H1155CN118852145APGDB_A019638PGDB_C001468PGDB_AS001039View
2D structure for PGDB_C001455
IC50-=9.23nM-GSPT1-NCI-H1155CN118852145APGDB_A020741PGDB_C001455PGDB_AS001039View
2D structure for PGDB_C001465
Dmax-=93.8%--GSPT1-HEK293CN118852145APGDB_A021184PGDB_C001465PGDB_AS002339View
2D structure for PGDB_C001466
Dmax-=93.24%--GSPT1-HEK293CN118852145APGDB_A022137PGDB_C001466PGDB_AS002339View
2D structure for PGDB_C001456
IC50-=72.7nM-CRBNCRBN-CN118852145APGDB_A023974PGDB_C001456PGDB_AS000570View
2D structure for PGDB_C001470
Dmax-=93.56%--GSPT1-HEK293CN118852145APGDB_A024704PGDB_C001470PGDB_AS002339View