Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C000378
10 activity records3 related patents
2D structure
Cc1cc(NC(=O)OCc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)ccc1ClCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 50-70 | % | - | - | - | - | MOLM-13 | CN117756818A | PGDB_A008676 | PGDB_C000378 | PGDB_AS000622 | View |
| IC50 | - | = | 100-1000 | nM | - | — | - | - | MOLM-13 | CN117756818A | PGDB_A008746 | PGDB_C000378 | PGDB_AS001583 | View |
| DC50 | - | <= | 30 | nM | - | — | - | - | CAL-51 | AU2022207648A1 | PGDB_A011413 | PGDB_C000378 | PGDB_AS002250 | View |
| IC50 | - | = | 57 | nM | - | — | CRBN | CRBN | NCI-H1155 | WO2024125437A1 | PGDB_A027361 | PGDB_C000378 | PGDB_AS001968 | View |
| % Degradation | - | < | 30 | % | - | - | - | - | MOLM-13 | CN117756818A | PGDB_A030177 | PGDB_C000378 | PGDB_AS002573 | View |
| IC50 | - | = | 100-1000 | nM | - | — | - | - | - | AU2022207648A1 | PGDB_A030426 | PGDB_C000378 | PGDB_AS000620 | View |
| IC50 | - | > | 2000 | nM | - | — | - | - | THP-1 | CN117756818A | PGDB_A042421 | PGDB_C000378 | PGDB_AS000638 | View |
| IC50 | - | = | 100-1000 | nM | - | — | BRD4/GSPT1 | - | NB4 | CN117756818A | PGDB_A058844 | PGDB_C000378 | PGDB_AS000935 | View |
| IC50 | - | > | 2000 | nM | - | — | BRD4/GSPT1 | - | Oci-AML3 | CN117756818A | PGDB_A059584 | PGDB_C000378 | PGDB_AS002081 | View |
| IC50 | - | < | 100 | nM | - | — | BRD4/GSPT1 | - | HL-60 | CN117756818A | PGDB_A077624 | PGDB_C000378 | PGDB_AS001357 | View |