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Compound
PGDB_C000398
8 activity records3 related patents
2D structure
N#Cc1cc(F)ccc1C1CN([C@H]2CCCC[C@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 0.024 | uM | - | — | CRBN | CRBN | HEK293T | CN117836288A | PGDB_A017358 | PGDB_C000398 | PGDB_AS001696 | View |
| % Degradation | - | < | 15 | % | 1 uM | 24 h | IKZF2 | CRBN | HEK293T | CN117836288A | PGDB_A024673 | PGDB_C000398 | PGDB_AS002458 | View |
| EC50 | - | = | 0.022 | uM | - | — | CRBN | CRBN | HEK293T | CN117836288A | PGDB_A029251 | PGDB_C000398 | PGDB_AS001696 | View |
| EC50 | - | = | 0.022 | uM | - | — | CRBN | CRBN | - | US20230265071A1 | PGDB_A042369 | PGDB_C000398 | PGDB_AS001482 | View |
| EC50 | - | = | 0.024 | uM | - | — | CRBN | CRBN | - | US20230265071A1 | PGDB_A048246 | PGDB_C000398 | PGDB_AS001482 | View |
| % Degradation | - | < | 15 | % | 1 uM | 24 h | IKZF2 | CRBN | HEK293T | AR126418A1 | PGDB_A053616 | PGDB_C000398 | PGDB_AS000416 | View |
| EC50 | - | = | 0.022 | uM | - | — | IKZF2 | CRBN | HEK293T | AR126418A1 | PGDB_A055739 | PGDB_C000398 | PGDB_AS001328 | View |
| % Degradation | - | < | 15 | % | 1 uM | 24 h | IKZF2 | - | HEK293T | US20230265071A1 | PGDB_A056414 | PGDB_C000398 | PGDB_AS000278 | View |