PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

25 activity records

Assay familybinding

Systemcell_based

Readoutbinding_percent

TargetCRBN

E3CRBN

Cell lineHEK-293

Activity compounds and values

Activity records

25 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A007466	PGDB_C001322	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A007582	PGDB_C001312	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A008318	PGDB_C001323	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A014164	PGDB_C001302	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	35	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A017463	PGDB_C001316	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A017992	PGDB_C001313	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A019903	PGDB_C001320	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A021182	PGDB_C001305	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A029502	PGDB_C001303	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A036555	PGDB_C001314	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A037179	PGDB_C001310	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A040989	PGDB_C001309	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	35	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A041391	PGDB_C001315	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A041549	PGDB_C001308	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A052924	PGDB_C001318	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A054110	PGDB_C001317	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	10	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A055696	PGDB_C001319	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A062440	PGDB_C001306	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	10	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A062889	PGDB_C001325	PGDB_AS000026	View
Relative binding	Ctrl @ 5uM	<	10	%	5 uM	1 h	CRBN	CRBN	HEK-293	KR20250075510A	PGDB_A064218	PGDB_C001301	PGDB_AS000026	View

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