PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

25 activity records

Assay familybinding

Systemcell_based

Readoutbinding_percent

TargetCRBN

E3CRBN

Cell lineHEK293

Activity compounds and values

Activity records

25 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
Relative binding	Ctrl @ 5uM	<	1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A011004	PGDB_C001303	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A011063	PGDB_C001314	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	35	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A014143	PGDB_C001315	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A014146	PGDB_C001305	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A015378	PGDB_C001308	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A015447	PGDB_C001309	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A017394	PGDB_C001320	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	10	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A030128	PGDB_C001319	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A030670	PGDB_C001306	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A031459	PGDB_C001323	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A033249	PGDB_C001317	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A034373	PGDB_C001322	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A035136	PGDB_C001318	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A041216	PGDB_C001312	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	10	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A041633	PGDB_C001325	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A042536	PGDB_C001324	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A044853	PGDB_C001313	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A048988	PGDB_C001321	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	0.1	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A050988	PGDB_C001302	PGDB_AS001966	View
Relative binding	Ctrl @ 5uM	<	10	%	5 uM	1 h	CRBN	CRBN	HEK293	WO2025110699A1	PGDB_A054824	PGDB_C001301	PGDB_AS001966	View

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