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Compound
PGDB_C001306
8 activity records2 related patents
2D structure
O=C1CCC(N2Cc3cc(C(=O)N4CCCC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Relative binding | Ctrl @ 5uM | < | 0.1 | % | 5 uM | 1 h | CRBN | CRBN | HEK293 | WO2025110699A1 | PGDB_A030670 | PGDB_C001306 | PGDB_AS001966 | View |
| % Degradation | - | = | 50-70 | % | 0.1 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A035642 | PGDB_C001306 | PGDB_AS002288 | View |
| % Degradation | - | = | 70-90 | % | 1 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A039941 | PGDB_C001306 | PGDB_AS001008 | View |
| % Degradation | - | = | 50-70 | % | 0.1 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A046445 | PGDB_C001306 | PGDB_AS001067 | View |
| % Degradation | - | = | 70-90 | % | 1 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A047648 | PGDB_C001306 | PGDB_AS000601 | View |
| % Degradation | - | = | 70-90 | % | 10 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A052378 | PGDB_C001306 | PGDB_AS001994 | View |
| Relative binding | Ctrl @ 5uM | < | 0.1 | % | 5 uM | 1 h | CRBN | CRBN | HEK-293 | KR20250075510A | PGDB_A062440 | PGDB_C001306 | PGDB_AS000026 | View |
| % Degradation | - | = | 70-90 | % | 10 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A071639 | PGDB_C001306 | PGDB_AS001448 | View |