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Compound
PGDB_C006610
7 activity records1 related patents
2D structure
Cc1cc(C)n2cc(CNc3cc(NC[C@H]4CCNC[C@@H]4O)nc4c(C(C)C)cnn34)nc2n1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selectivity index | CDK7 / CDK12 | = | 23 | fold | - | — | - | - | - | CN114929708B | PGDB_A030194 | PGDB_C006610 | PGDB_AS002236 | View |
| IC50 | - | = | 340 | nM | - | — | CDK12 | - | A673 | CN114929708B | PGDB_A043275 | PGDB_C006610 | PGDB_AS002570 | View |
| IC50 | - | = | 21 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A051861 | PGDB_C006610 | PGDB_AS001066 | View |
| IC50 | - | = | 21 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A055505 | PGDB_C006610 | PGDB_AS001187 | View |
| IC50 | - | = | 21 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A056695 | PGDB_C006610 | PGDB_AS001268 | View |
| IC50 | - | = | 340 | nM | - | — | CDK12 | - | A673 | CN114929708B | PGDB_A075544 | PGDB_C006610 | PGDB_AS002202 | View |
| IC50 | - | = | 484 | nM | - | — | CDK7 | - | - | CN114929708B | PGDB_A075579 | PGDB_C006610 | PGDB_AS002150 | View |