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SIMM · NJU
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·
SIMM · NJU
Target
KRAS
1,754 activity records
643 compounds
7 patents
Target summary
Target ID
PGDB_T000011
Name
KRAS
Gene symbol
KRAS
Protein name
GTPase KRas
UniProt ID
P01116
Role
binding_partner | degradation_target | primary_target
Compounds
643
Activity records
1,754
Assays
54
Patents
7
Activity compounds and values
Activity records
1,754 records
Structure
Metric
Control
Relation
Value
Unit
Concentration
Time
Target
E3
Cell line
Patent
Record ID
Compound
Assay
Details
Dmax
-
=
71
%
-
18 h
KRAS
-
-
WO2026114958A1
PGDB_A000080
PGDB_C031947
PGDB_AS001227
View
DC50
-
=
2.9
nM
-
—
KRAS
-
-
WO2026114958A1
PGDB_A000102
PGDB_C031991
PGDB_AS002526
View
IC50
-
=
11.7
nM
-
—
KRAS
CRBN
H358
WO2026114958A1
PGDB_A000116
PGDB_C031956
PGDB_AS000990
View
IC50
-
=
14.4
nM
-
—
KRAS
CRBN
H358
WO2026114958A1
PGDB_A000124
PGDB_C031964
PGDB_AS000990
View
IC50
-
=
3.7
nM
-
—
KRAS
CRBN
H358
WO2026114958A1
PGDB_A000165
PGDB_C031967
PGDB_AS000990
View
Dmax
-
=
82
%
-
18 h
KRAS
-
-
WO2026114958A1
PGDB_A000166
PGDB_C031975
PGDB_AS001227
View
IC50
-
=
5.9
nM
-
—
KRAS
CRBN
H358
WO2026114958A1
PGDB_A000195
PGDB_C031982
PGDB_AS000990
View
Dmax
-
=
79
%
-
18 h
KRAS
-
-
WO2026114958A1
PGDB_A000212
PGDB_C031966
PGDB_AS001980
View
DC50
-
=
2
nM
-
—
KRAS
-
-
WO2026114958A1
PGDB_A000262
PGDB_C031972
PGDB_AS001045
View
DC50
-
=
3.1
nM
-
—
KRAS
-
-
WO2026114958A1
PGDB_A000381
PGDB_C031947
PGDB_AS001045
View
DC50
-
=
1.4
nM
-
—
KRAS
-
-
WO2026114958A1
PGDB_A000388
PGDB_C031991
PGDB_AS001045
View
Dmax
-
=
66
%
-
18 h
KRAS
-
-
WO2026114958A1
PGDB_A000408
PGDB_C031989
PGDB_AS001980
View
Dmax
-
=
70
%
-
18 h
KRAS
-
-
WO2026114958A1
PGDB_A000488
PGDB_C031986
PGDB_AS001227
View
IC50
-
=
2
nM
-
—
KRAS
-
-
WO2026114957A1
PGDB_A000494
PGDB_C031999
PGDB_AS000596
View
DC50
-
=
2.7
nM
-
—
KRAS
-
-
WO2026114958A1
PGDB_A000523
PGDB_C031984
PGDB_AS001045
View
DC50
-
=
3.6
nM
-
—
KRAS
-
-
WO2026114958A1
PGDB_A000531
PGDB_C031978
PGDB_AS002526
View
DC50
-
=
14.2
nM
-
—
KRAS
-
-
WO2026114958A1
PGDB_A000551
PGDB_C031966
PGDB_AS002526
View
DC50
-
=
9.8
nM
-
—
KRAS
-
-
WO2026114958A1
PGDB_A000593
PGDB_C031954
PGDB_AS002526
View
IC50
-
=
1.3
nM
-
—
KRAS
CRBN
H358
WO2026114958A1
PGDB_A000601
PGDB_C031942
PGDB_AS000990
View
Dmax
-
=
77
%
-
18 h
KRAS
-
-
WO2026114958A1
PGDB_A000696
PGDB_C031963
PGDB_AS001980
View