Summary
AssigneeBeijing Hospital
Filing years2023
Patents2
Compounds42
Activity records108
Patent families2
Targets3
Assay familiesdegradation, viability
Activity metricsIC50, degradation
Overview

Target distribution and active-compound trend

Target distribution

239 activity records

4 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

021422024
Activity compounds and values

Activity records

239 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C000343
IC50-=2000-4000nM---THP-1CN117683022APGDB_A008269PGDB_C000343PGDB_AS000289View
2D structure for PGDB_C000352
IC50-=2000-4000nM---THP-1CN117683022APGDB_A008760PGDB_C000352PGDB_AS000289View
2D structure for PGDB_C000346
% Degradation-=30-60%--BRD4--CN117683022APGDB_A009721PGDB_C000346PGDB_AS002272View
2D structure for PGDB_C000355
% Degradation-=60-80%--GSPT1--CN117683022APGDB_A010675PGDB_C000355PGDB_AS001783View
2D structure for PGDB_C000357
IC50-=5.3nM---THP-1CN117683022APGDB_A011310PGDB_C000357PGDB_AS000289View
2D structure for PGDB_C000351
IC50-=2000-4000nM---THP-1CN117683022APGDB_A011689PGDB_C000351PGDB_AS000289View
2D structure for PGDB_C000344
IC50-=200-2000nM---RajiCN117683022APGDB_A011896PGDB_C000344PGDB_AS000751View
2D structure for PGDB_C000340
% Degradation-=10-30%--GSPT1--CN117683022APGDB_A011973PGDB_C000340PGDB_AS001783View
2D structure for PGDB_C000348
% Degradation-=10-30%--GSPT1--CN117683022APGDB_A013934PGDB_C000348PGDB_AS001783View
2D structure for PGDB_C000343
IC50-=200-2000nM---RajiCN117683022APGDB_A014595PGDB_C000343PGDB_AS000751View
2D structure for PGDB_C000354
% Degradation-=30-60%--BRD4--CN117683022APGDB_A016873PGDB_C000354PGDB_AS002272View
2D structure for PGDB_C000357
Apoptosis->60%----CN117683022APGDB_A018415PGDB_C000357PGDB_AS001538View
2D structure for PGDB_C000059
% Degradation-=10-30%--BRD4--CN117683022APGDB_A019080PGDB_C000059PGDB_AS002272View
2D structure for PGDB_C000059
IC50->4000nM---RajiCN117683022APGDB_A020158PGDB_C000059PGDB_AS000751View
2D structure for PGDB_C000353
% Degradation-=30-60%--BRD4--CN117683022APGDB_A021516PGDB_C000353PGDB_AS002272View
2D structure for PGDB_C000352
IC50-=200-2000nM---RajiCN117683022APGDB_A023328PGDB_C000352PGDB_AS000751View
2D structure for PGDB_C000347
% Degradation-=30-60%--GSPT1--CN117683022APGDB_A023402PGDB_C000347PGDB_AS001783View
2D structure for PGDB_C000341
IC50-=2000-4000nM---THP-1CN117683022APGDB_A024894PGDB_C000341PGDB_AS000289View
2D structure for PGDB_C000059
IC50->4000nM---THP-1CN117683022APGDB_A024897PGDB_C000059PGDB_AS000289View
2D structure for PGDB_C000356
IC50-=67.3nM---RajiCN117683022APGDB_A026802PGDB_C000356PGDB_AS000751View