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Compound
PGDB_C011599
10 activity records1 related patents
2D structure
CCn1c2c(-c3cc(C#CCN4CCCCC4)cnc3C(C)OC)c3cc(ccc31)-c1csc(n1)CC(NC(=O)C1C(C)C1C)C(=O)N1NC(C(=O)OCC(C)(C)C2)C2CC1C2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 1-10 | nM | - | — | - | - | AsPC-1 | WO2025214350A1 | PGDB_A015033 | PGDB_C011599 | PGDB_AS001410 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A016221 | PGDB_C011599 | PGDB_AS000307 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A017262 | PGDB_C011599 | PGDB_AS000928 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | HPAC | WO2025214350A1 | PGDB_A027994 | PGDB_C011599 | PGDB_AS002124 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | AGS | WO2025214350A1 | PGDB_A034226 | PGDB_C011599 | PGDB_AS000218 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A034844 | PGDB_C011599 | PGDB_AS002054 | View |
| IC50 | - | <= | 1 | nM | - | — | KRAS | - | NCI-H358 | WO2025214350A1 | PGDB_A042016 | PGDB_C011599 | PGDB_AS001442 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A048755 | PGDB_C011599 | PGDB_AS000791 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A066993 | PGDB_C011599 | PGDB_AS001818 | View |
| IC50 | - | <= | 1 | nM | - | — | KRAS | - | SW620 | WO2025214350A1 | PGDB_A067039 | PGDB_C011599 | PGDB_AS001156 | View |