Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C025807
11 activity records1 related patents
2D structure
Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@H]1CCN(Cc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C[C@H]1FCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | < | 50 | nM | - | — | BTK | - | VCaP | CN116239566A | PGDB_A009236 | PGDB_C025807 | PGDB_AS001439 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | MM.1S | CN116239566A | PGDB_A032229 | PGDB_C025807 | PGDB_AS002551 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | THP-1 | CN116239566A | PGDB_A039218 | PGDB_C025807 | PGDB_AS000486 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | CCRF-CEM | CN116239566A | PGDB_A045496 | PGDB_C025807 | PGDB_AS000469 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | CRBN | Mino | CN116239566A | PGDB_A054274 | PGDB_C025807 | PGDB_AS000540 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | NCI-H1975 | CN116239566A | PGDB_A056045 | PGDB_C025807 | PGDB_AS000844 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | MDA-MB-231 | CN116239566A | PGDB_A056639 | PGDB_C025807 | PGDB_AS001770 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | CRBN | 22Rv1 | CN116239566A | PGDB_A058104 | PGDB_C025807 | PGDB_AS001253 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | MV-4-11 | CN116239566A | PGDB_A066724 | PGDB_C025807 | PGDB_AS000080 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | Kasumi-1 | CN116239566A | PGDB_A073517 | PGDB_C025807 | PGDB_AS000510 | View |
| IC50 | - | < | 50 | nM | - | — | BTK | - | JeKo-1 | CN116239566A | PGDB_A075596 | PGDB_C025807 | PGDB_AS000420 | View |