PatGlueDB | Molecular Glue Patent Bioactivity Database

Target summary

Target IDPGDB_T000027

NameAR

Gene symbolAR

Protein nameAndrogen receptor

UniProt IDP10275

Roledegradation_target | primary_target

Compounds1,772

Activity records8,038

Assays61

Patents14

Activity compounds and values

Activity records

8,038 records

	Control		Value		Concentration	Time					Record ID	Compound	Assay	Details
DC50	-	=	10000	nM	-	—	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000005	PGDB_C032272	PGDB_AS001413	View
% Degradation	-	=	65	%	100 nM	-	AR	-	LNCaPFGC	WO2026061104A1	PGDB_A000006	PGDB_C029932	PGDB_AS002389	View
DC50	-	=	10000	nM	-	—	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000008	PGDB_C032265	PGDB_AS001413	View
% Degradation	-	=	96	%	50 nM	-	AR	-	VCaP	WO2026061104A1	PGDB_A000012	PGDB_C029984	PGDB_AS001838	View
% Degradation	-	=	79	%	50 nM	-	AR	-	VCaP	WO2026061104A1	PGDB_A000013	PGDB_C029769	PGDB_AS001838	View
% Degradation	-	=	70	%	5 nM	-	AR	-	VCaP	WO2026061104A1	PGDB_A000017	PGDB_C029736	PGDB_AS001354	View
IC50	-	=	0.53	nM	-	—	AR	-	LNCaPFGC	WO2026061104A1	PGDB_A000020	PGDB_C029952	PGDB_AS000195	View
% Degradation	-	=	93	%	100 nM	-	AR	-	LNCaPFGC	WO2026061104A1	PGDB_A000025	PGDB_C029736	PGDB_AS002389	View
IC50	-	=	0.0065	nM	-	—	AR	-	VCaP	WO2026061104A1	PGDB_A000029	PGDB_C029789	PGDB_AS000481	View
Dmax	-	=	82.64	%	-	-	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000031	PGDB_C032405	PGDB_AS002073	View
% Degradation	-	=	81	%	100 nM	-	AR	-	LNCaPFGC	WO2026061104A1	PGDB_A000032	PGDB_C029741	PGDB_AS002389	View
% Degradation	-	=	86	%	100 nM	-	AR	-	LNCaPFGC	WO2026061104A1	PGDB_A000035	PGDB_C029794	PGDB_AS002389	View
% Degradation	-	=	82	%	50 nM	-	AR	-	VCaP	WO2026061104A1	PGDB_A000037	PGDB_C030063	PGDB_AS001838	View
% Degradation	-	=	48	%	10 nM	-	AR	-	LNCaPFGC	WO2026061104A1	PGDB_A000040	PGDB_C029743	PGDB_AS002463	View
% Degradation	-	=	18	%	10 nM	-	AR	-	LNCaPFGC	WO2026061104A1	PGDB_A000042	PGDB_C030080	PGDB_AS002463	View
% Degradation	-	=	75	%	50 nM	-	AR	-	VCaP	WO2026061104A1	PGDB_A000046	PGDB_C029766	PGDB_AS001838	View
% Degradation	-	=	40	%	100 nM	-	AR	-	LNCaPFGC	WO2026061104A1	PGDB_A000049	PGDB_C029959	PGDB_AS002389	View
DC50	-	=	43.4	nM	-	—	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000050	PGDB_C032365	PGDB_AS001413	View
Dmax	-	=	84.53	%	-	-	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000053	PGDB_C032432	PGDB_AS002073	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA4	-	MV-4-11	WO2026061475A1	PGDB_A000055	PGDB_C030482	PGDB_AS002340	View

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