Assignee profile

Genentech

Coverage of patents, compounds and activity records linked to this assignee.

1 patents216 compounds1,036 activity records
Summary
AssigneeGenentech
Filing years2024
Patents1
Compounds216
Activity records1,036
Patent families1
Targets3
Assay familiesbinding, degradation
Activity metricsDmax, IC50, Kd
Overview

Target distribution and active-compound trend

Target distribution

1,036 activity records

3 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

01082162025
Activity compounds and values

Activity records

1,036 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C008122
Kd-=0.13uM-—CRBNCRBN-WO2025043225PGDB_A007039PGDB_C008122PGDB_AS000522View
2D structure for PGDB_C008126
IC50-=1uM-—GSPT1CRBNHEK293WO2025043225PGDB_A007083PGDB_C008126PGDB_AS000357View
2D structure for PGDB_C007941
IC50-=0.084uM-—CRBNCRBN-WO2025043225PGDB_A007254PGDB_C007941PGDB_AS001908View
2D structure for PGDB_C007983
Kd-=0.13uM-—CRBNCRBN-WO2025043225PGDB_A007345PGDB_C007983PGDB_AS000368View
2D structure for PGDB_C008075
Dmax-=13%--GSPT1-HEK293WO2025043225PGDB_A007619PGDB_C008075PGDB_AS000025View
2D structure for PGDB_C008113
Dmax-=74%--CDK2-HEK293WO2025043225PGDB_A007731PGDB_C008113PGDB_AS000554View
2D structure for PGDB_C008029
Dmax-=40%--CDK2-HEK293WO2025043225PGDB_A007954PGDB_C008029PGDB_AS000735View
2D structure for PGDB_C007932
IC50-=31uM-—GSPT1-HEK293WO2025043225PGDB_A007981PGDB_C007932PGDB_AS002153View
2D structure for PGDB_C008048
Kd-=0.017uM-—CRBNCRBN-WO2025043225PGDB_A008203PGDB_C008048PGDB_AS000522View
2D structure for PGDB_C008112
Kd-=0.047uM-—CRBNCRBN-WO2025043225PGDB_A008272PGDB_C008112PGDB_AS000522View
2D structure for PGDB_C007982
Dmax-=4.4%--GSPT1-HEK293WO2025043225PGDB_A008447PGDB_C007982PGDB_AS000429View
2D structure for PGDB_C008072
IC50-=10uM-—GSPT1CRBNHEK293WO2025043225PGDB_A008633PGDB_C008072PGDB_AS000357View
2D structure for PGDB_C008069
IC50-=10uM-—GSPT1CRBNHEK293WO2025043225PGDB_A008689PGDB_C008069PGDB_AS000357View
2D structure for PGDB_C008095
Dmax-=17%--GSPT1-HEK293WO2025043225PGDB_A008747PGDB_C008095PGDB_AS000025View
2D structure for PGDB_C008028
Dmax-=39%--CDK2-HEK293WO2025043225PGDB_A008964PGDB_C008028PGDB_AS000735View
2D structure for PGDB_C008082
Kd-=1.3uM-—CRBNCRBN-WO2025043225PGDB_A009001PGDB_C008082PGDB_AS000522View
2D structure for PGDB_C008081
IC50-=0.0078uM-—CDK2-HEK293WO2025043225PGDB_A009011PGDB_C008081PGDB_AS002100View
2D structure for PGDB_C008067
Dmax-=17%--GSPT1-HEK293WO2025043225PGDB_A009048PGDB_C008067PGDB_AS000025View
2D structure for PGDB_C007979
Dmax-=0.71%--GSPT1-HEK293WO2025043225PGDB_A009108PGDB_C007979PGDB_AS000429View
2D structure for PGDB_C007993
Dmax-=62%--CDK2-HEK293WO2025043225PGDB_A009307PGDB_C007993PGDB_AS000677View
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