PatGlueDB | Molecular Glue Patent Bioactivity Database

Target summary

Target IDPGDB_T000041

NameCDK2

Gene symbolCDK2

Protein nameCyclin-dependent kinase 2

UniProt IDP24941

Roleassay_marker | degradation_target | primary_target

Compounds520

Activity records920

Assays27

Patents8

Activity compounds and values

Activity records

920 records

	Control		Value		Concentration	Time					Record ID	Compound	Assay	Details
DC50	-	=	12.02264434617413	nM	-	—	CDK2	-	HEK293T	WO2026064643A1	PGDB_A000290	PGDB_C011110	PGDB_AS001728	View
DC50	-	=	66.06934480075964	nM	-	—	CDK2	-	HEK293T	WO2026064643A1	PGDB_A000319	PGDB_C011112	PGDB_AS001728	View
DC50	-	=	3.019951720402019	nM	-	—	CDK2	-	HEK293T	WO2026064643A1	PGDB_A001507	PGDB_C030652	PGDB_AS001728	View
DC50	-	=	21.87761623949552	nM	-	—	CDK2	-	HEK293T	WO2026064643A1	PGDB_A002618	PGDB_C030651	PGDB_AS001728	View
Dmax	-	=	59.6	%	10 uM	-	CDK2	-	HEK293T	WO2026064643A1	PGDB_A004323	PGDB_C030651	PGDB_AS000752	View
Dmax	-	=	49.2	%	10 uM	-	CDK2	-	HEK293T	WO2026064643A1	PGDB_A004371	PGDB_C011112	PGDB_AS000752	View
Dmax	-	=	56.9	%	10 uM	-	CDK2	-	HEK293T	WO2026064643A1	PGDB_A004500	PGDB_C026003	PGDB_AS000752	View
Dmax	-	=	75.4	%	10 uM	-	CDK2	-	HEK293T	WO2026064643A1	PGDB_A005351	PGDB_C030654	PGDB_AS000752	View
DC50	-	=	10	nM	-	—	CDK2	-	HEK293T	WO2026064643A1	PGDB_A005853	PGDB_C026003	PGDB_AS001728	View
Dmax	-	=	80.7	%	10 uM	-	CDK2	-	HEK293T	WO2026064643A1	PGDB_A005858	PGDB_C030652	PGDB_AS000752	View
DC50	-	=	0.3235936569296281	nM	-	—	CDK2	-	HEK293T	WO2026064643A1	PGDB_A006684	PGDB_C030654	PGDB_AS001728	View
Dmax	-	=	45.6	%	-	-	CDK2	-	HEK293	WO2025181261A1	PGDB_A007262	PGDB_C011348	PGDB_AS000913	View
Dmax	-	=	56.6	%	-	-	CDK2	-	HEK293	WO2025181261A1	PGDB_A007268	PGDB_C011366	PGDB_AS000913	View
DC50	-	=	9.6	nM	-	—	CDK2	-	HEK293	WO2025224262A1	PGDB_A007333	PGDB_C011769	PGDB_AS001903	View
Dmax	-	=	47.5	%	-	24 h	CDK2	-	HEK293	WO2025224249A1	PGDB_A007358	PGDB_C011745	PGDB_AS002358	View
Dmax	-	=	61.9	%	-	24 h	CDK2	-	HEK293	WO2025224249A1	PGDB_A007551	PGDB_C011755	PGDB_AS002358	View
Dmax	-	=	52.6	%	-	-	CDK2	-	HEK293	WO2025181261A1	PGDB_A007710	PGDB_C011363	PGDB_AS000913	View
Dmax	-	=	74	%	10 uM	6 h	CDK2	-	HEK293	WO2025043225	PGDB_A007731	PGDB_C008113	PGDB_AS000554	View
Dmax	-	=	67.6	%	-	24 h	CDK2	-	HEK293	WO2025090727A1	PGDB_A007852	PGDB_C010135	PGDB_AS002016	View
Dmax	-	=	52	%	-	-	CDK2	-	HEK293	WO2025181261A1	PGDB_A007921	PGDB_C011290	PGDB_AS000913	View

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