PatGlueDB | Molecular Glue Patent Bioactivity Database

Target summary

Target IDPGDB_T000035

NameVAV1

Gene symbolVAV1

Protein nameProto-oncogene vav

UniProt IDP15498

Roledegradation_target | primary_target

Compounds1,192

Activity records2,408

Assays59

Patents16

Activity compounds and values

Activity records

2,408 records

	Control		Value		Concentration	Time					Record ID	Compound	Assay	Details
DC50	-	=	2.3	nM	-	—	VAV1	-	-	WO2026051943A1	PGDB_A000001	PGDB_C029684	PGDB_AS001440	View
DC50	-	=	5	nM	-	—	VAV1	-	-	WO2026051943A1	PGDB_A000016	PGDB_C029462	PGDB_AS001440	View
DC50	-	=	2	nM	-	—	VAV1	-	-	WO2026119120A1	PGDB_A000026	PGDB_C032005	PGDB_AS001984	View
IC50	-	=	87.83	nM	-	—	VAV1	-	REC-1	WO2026103798A1	PGDB_A000030	PGDB_C031353	PGDB_AS000941	View
DC50	-	<	100	nM	-	—	VAV1	-	-	WO2026119245A1	PGDB_A000033	PGDB_C032202	PGDB_AS001875	View
IC50	-	=	161.56	nM	-	—	VAV1	-	REC-1	WO2026103798A1	PGDB_A000041	PGDB_C031339	PGDB_AS000941	View
DC50	-	=	4.2	nM	-	—	VAV1	-	-	WO2026119120A1	PGDB_A000043	PGDB_C032057	PGDB_AS001984	View
Dmax	-	=	92	%	Concentration range: 1000 nM	-	VAV1	-	Jurkat	WO2026061428A1	PGDB_A000048	PGDB_C024745	PGDB_AS000765	View
DC50	-	<=	20	nM	-	—	VAV1	-	-	WO2026114368A1	PGDB_A000051	PGDB_C031883	PGDB_AS000780	View
DC50	-	=	45.09	nM	-	—	VAV1	-	293T-VAV1-FLAG	WO2026103873A1	PGDB_A000063	PGDB_C031440	PGDB_AS000831	View
DC50	-	=	13.11	nM	-	—	VAV1	-	293T-VAV1-FLAG	WO2026103873A1	PGDB_A000064	PGDB_C031456	PGDB_AS000831	View
Dmax	-	=	96.1	%	Concentration range: 1000 nM	-	VAV1	-	Jurkat	WO2026061428A1	PGDB_A000067	PGDB_C024811	PGDB_AS000765	View
Dmax	-	=	98.44	%	Concentration series: 10 uM, 1 uM	-	VAV1	-	-	WO2026051943A1	PGDB_A000079	PGDB_C029586	PGDB_AS000777	View
DC50	-	=	2.69	nM	-	—	VAV1	-	-	WO2026051943A1	PGDB_A000082	PGDB_C029490	PGDB_AS001440	View
IC50	-	<=	1	nM	-	—	VAV1	-	primaryT	WO2026114368A1	PGDB_A000090	PGDB_C031870	PGDB_AS001463	View
Dmax	-	=	96.9	%	0.02 nM	-	VAV1	-	-	WO2026119120A1	PGDB_A000096	PGDB_C032056	PGDB_AS000657	View
DC50	-	<=	20	nM	-	—	VAV1	-	-	WO2026114368A1	PGDB_A000100	PGDB_C031873	PGDB_AS000780	View
DC50	-	<	100	nM	-	—	VAV1	-	-	WO2026119245A1	PGDB_A000104	PGDB_C032078	PGDB_AS001875	View
IC50	-	<=	1	nM	-	—	VAV1	-	primaryT	WO2026114367A1	PGDB_A000119	PGDB_C031769	PGDB_AS000152	View
IC50	-	=	0.034	nM	-	—	VAV1	-	pan-T	WO2026051943A1	PGDB_A000131	PGDB_C029568	PGDB_AS000112	View

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